Best Appetite Suppressants 2025

What Are Appetite Suppressants?

Appetite suppressant pills are among the most popular supplements for those looking to lose weight or burn fat. Their purpose is to increase satiety and induce a feeling of fullness, which will help to suppress appetite and prevent hunger and food cravings. 

There's nothing worse when you're trying to lose weight than feeling hungry all the time and appetite suppressants can make it easier to stick to a healthy diet. This means you likely won't snack, will consume fewer calories, and can keep your weight loss journey on track. They're not a magic bullet, and natural appetite suppressant supplements are only going to go so far, but using them in the right way you can help prevent yourself overeating or to prevent your worst snacking habits. 

With appetite suppressing supplements containing such a wide range of unusual ingredients though, it can be challenging to work out which are the best to use. That is why we have done the hard work for you, and determined the very best appetite suppressants available in 2025.

Top Picks

Angel Slimmies - Best Gummy Appetite Suppressant
Instant Knockout - Fastest Acting Appetite Suppressant
Hunter Burn - Best Premium Appetite Suppressant
Hourglass Fit - Best Appetite Supressant For Women

The Best Appetite Suppressant Supplements

Appetite suppressing supplements are all designed with the same core goal in mind, to help you control hunger. However, with the various ingredients they use, many appetite suppressants will also be designed for a specific group or to provide additional benefits. 

For example, men and women will often require slightly different things to achieve optimal results, thanks to their genetics. People like athletes will also require effects like a boost in energy, to help keep them competitive while they are on a low calorie intake. 

That is why our list of the best appetite suppressant supplements will not only include the best appetite suppressant overall, but will also include choices for some of the other top requirements people may have for them as well.

Types Of Appetite Suppressant

There are two main categories of appetite suppressants: prescription and over-the-counter (OTC). Prescription appetite suppressants are typically stronger and require a doctor's prescription, while OTC options are available without a prescription.

It is worth noting that some perscription and over the counter options function in similar ways and there isn't a great deal of difference for example Plenity (a well known perscription appetite suppressant) functions by containing non digestable fibers (meaning they're near enough 0 caloreis) which swell up about 80X larger in the stomach when you drink some water making you feel full. This is functionally no different than the mechanism behind glucomannan, which swells up 50X larger, but is available as an over the counter appetite suppressant and usually costs signficantly less. 

The Best Appetite Suppressant Over The Counter

To begin with let's have a look at the OTC options, and things that you can get yourself without needing to see a medical proffessional. We'll look at the other options a little later. Insurance coverage for weight loss is of course spotty at best, so in many cases commercial options are functionally as effective and substantially cheaper, especially if they work by expanding in the stomach.

Glucomannan (Konjac Root Extract) - Glucomannan is a type of dietary fiber that comes from the roots of the elephant yam plant that is native to East Asia. It helps to suppress appetite as it is very low in calories but will expand to take up a huge amount of space in your gut when it comes in contact with water. This is mainly used to reduce hunger pains and stop you from wanting to eat, helping to keep your calorie intake down (1). It can also slow the rate that food is released from your gut too though. This gives you longer to process it, ensuring everything else available is used first. 
This combination will prevent weight gain, encourage fat burning when energy is required, and make optimum use of the food you consume. It is also ideal for helping people to stick to a healthy diet. Glucomannan is most effective when taken 1 hour before eating with water.

White Kidney Bean Extract - White kidney bean extract is a compound rich in dietary fiber that is taken from legumes native to South America. Like most types of dietary fiber, white kidney bean extract has a number of effects on the digestive system. Similar to glucomannan, it can swell in the gut to make you feel full, although not to the same extent. White kidney bean extract also effects the conversion of carbs into sugar. This will not only optimise your nutrient usage, further helping with hunger control, but it will also prevent weight gain and fat storage from occurring, which will help you lose weight much faster (2). 

Caffiene - Research has shown that consuming caffeine before a meal can influence stomach emptying, appetite hormones, and feelings of hunger. This effect lasts about 4 hours, but it does have other benefits to dieting besides appetite suppression. For example, when we diet our body subconciously tells us to move less, we do this without knowing and thus we actually burn slightly less calories through the day. Caffeine being a stimulant also helps mitigate this.

Chromium Picolinate - Chromium picolinate is a compound formed when the amino acid derivative of chromium is mixed with picolinic acid. Research has shown that it can be effective for appetite suppression as it raises serotonin levels, which will help to keep your food cravings in check. 
It also has the ability to enhance the activity of insulin receptors in your brain. This helps to lower blood glucose levels, preventing blood sugar spikes, while breaking down the nutrients you consume more effectively to avoid weight gain (2). 
Other benefits of chromium picolinate that are useful for weight loss include preserving muscle mass, enhancing cognitive functions, boosting energy, and improving your quality of sleep. 

5-HTP - 5-HTP is the abbreviated name for the chemical known as 5-hydroxytryptophan, which is a type of naturally occurring amino acid. Its use as an appetite suppressant comes from the fact that it is also a precursor to the neurotransmitter serotonin. 
Much like with chromium picolinate, it can therefore induce feelings of fullness and satiety, which will prevent you from giving in to your food cravings (4). 
Other benefits of 5-HTP include an ability to boost mood, reduce anxiety, increase relaxation, enhance your quality of sleep, and combat depression. All of these functions can then have a beneficial effect on weight loss and help you to control hunger in their own right. 

Green Tea Extract (EGCG) -  Green tea extract has been widely studied for its weight loss benefits. It contains caffeine and catechins, such as epigallocatechin gallate (EGCG), which can boost metabolism, increase fat burning, and suppress appetite. The caffeine content is relatively low, to low to function by itself, as you need about 100mg per serving for the effect, and green tea has about 20% of this at best. So you'll want to look for the EGCG content to be standardized specifically. It's often found in combination with caffeine in commercial weight loss aids.

Gymnema sylvestre - This herb that has mostly been studied for its anti-diabetic properties. But, more recent studies suggest it can aid in weight loss by reducing sugar cravings and appetite. However, it turns out, what's actually happening is the active compounds in Gymnema sylvestre, called gymnemic acids, can block the sweetness of food, reducing the taste of sugar in the mouth. It doesn't particularly stop you craving as the initial theories suggested, but it does make sugar less satisfying in general training people out of the craving. It's functionally akin to the method of adding polish to a persons nails, to make them taste bad as a way to prevent nail biting.

NB:  Whilst Orlistat is commonly associated with weight loss as both an over the counter and perscription option does not actually supress hunger. It is something known as a lipase inhibitor, and designed to prevent the absorbtion of fat in the digestive tract, it's efficacy is highly dependant on diet.

Instant Knockout Cut - Best Appetite Suppressant Pills

Instant Knockout Cut is a fat burner made specifically for top level combat sport competitors, such as professional boxers and MMA fighters. Its formula is perfect to help you quickly lose weight and lower your body fat while maintaining muscle mass in the build up to a fight. 

It contains only natural ingredients that have been scientifically tested and proven. This ensures it can offer maximum fat burning and improve your physical performance, without the use of anything that could cause you to fail a drug test. It's heavy on glucomannan and caffeine, which we covered already as two of the most effective appetite suppression ingredients.

What Is In Instant Knockout Cut? 

Instant Knockout Cut contains black pepper extract, caffeine, cayenne pepper, glucomannan, green tea extract, l-theanine, vitamin b6, vitamin b12, and vitamin d3. Each is chosen to both produce results and work in synchronicity with the other ingredients in the formula. 

The low calorie glucomannan will absorb water in your gut, suppressing your appetite and stopping you from over eating. The green tea extract will then improve digestion to ensure no bloating occurs as a result of this as well as adding some hunger reducing effects of it's own. 

Caffeine boosts thermogenesis, speeding up the metabolism of fatty acids, giving you more energy and helping you to train harder as well as being a strong appetite suppressant (5). The l-theanine then helps to prevent the crashes and sleep issues sometimes associated with stimulants (6). 

The 2 pepper extracts will further enhance metabolism and thermogenesis, while boosting the absorption of all the other ingredients in the supplement (7)(8). Whilst these sorts of "metabolism boosting" ingredients are generally far less effective, it's a nice extra that we doesn't hurt, and as Instant Knockout represents a good deal even without those we have no complaints. The vitamins then ensure your body is fully functional and healthy throughout the weight loss process, and seeing as they play a role in ghrelin (the hunger hormone) regulation, they're solid ingredients.

Hourglass Fit - Best Appetite Suppressant Pills For Women

The Best Appetite Suppressant IngredientsHourglass Fit is a carefully designed weight loss supplement that focuses on giving you the ability to control hunger, so you can stick to a healthy diet and stay on track. 

Unlike many appetite suppressant supplements that simply work by focusing on the physical causes of hunger, Hourglass Fit targets the mental side of it as well. This should allow users to completely forget about their food cravings, without any discomfort or side effects. 

What Is In Hourglass Fit? 

Hourglass Fit is fuelled by a potent 3,000 mg of konjac root extract (glucomannan), which is among the strongest doses you will find in any appetite suppressants on the market. This is then supported by 150 mg of 5-HTP and 125µg of chromium. 

The glucomannan will supress appetite physically by taking up space in your gut. The 5-HTP and chromium, on the other hand, effect serotonin levels in the brain, to make you feel happy and satiated. This targets the issue from both sides to completely remove all cravings. 

The inclusion of black pepper extract and cayenne pepper extract will enhance these effects, while mildly elevating the fat burning process. 

The Hourglass Fit formula is then rounded off with a selection of vitamins and minerals that includes vitamin B2, vitamin B6, vitamin B12, and zinc. 

These provide a range of effects, from further supressing appetite and boosting the bioavailability of the other ingredients to enhancing your health and wellness.

Visit hourglassfit.com

Hourglass Fit is the best appetite suppressant for those who simply can't get their mind off of food while on a diet. Its glucomannan will help to fill you up physically, while the rest of the ingredients in its formula will trick your brain into forgetting about your cravings.

Its other ingredients then gently help you lose weight in their own right, ensuring the physical results are greater than you could achieve on your own.

Customers Hourglass Appetitie Suppressant Pill Reviews

Much like Hunter, Hourglass has a fantastic track record with it's customers. And they too don't use unrealistic before and after photos and keep their claims plausable. This tends to lead to pretty good reviews as most people know that it's supposed to make weight loss easier, not be a magic pill. 

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Pros	Cons
Offers both mental and physical appetite suppressing effects  Includes high doses of all of its active ingredients  Only uses ingredients that have been scientifically researched and proven  Suitable for vegans  Includes free worldwide shipping	Works almost solely as an appetite suppressant so may not be ideal for people who need assistance with other weight loss issues

Criteria	Rating
Appetite Supressant	10/10
Craving Support	10/10
Other Benefits	6/10
Customer Satisfaction	10/10
Ingredients Quality	9/10
Value	9.5/10
Recommended	9/10

Hunter Burn - Best Premium Appetite Suppressant Pills 

Hunter Burn is a high end fat burning supplement that focuses heavily on suppressing appetite above all else in order to achieve results. Every dose is made using generous doses of each of the ingredients, to ensure it offers maximum efficacy while staying within the safe limits. 

The target audience of Hunter Burn is those who have a hard time controlling their food cravings. Using its potent appetite suppressing abilities, it is designed to take your mind off of hunger, so that the natural fat burning process can take place.

What's In Hunter Burn? 

The Hunter Burn formula is designed around an incredible 3,000 mg of konjac root extract in every serving, making it equivilant to the size of one and half large bagels in your stomach and 0 calories, so you'll feel full. This is then supported by an almost equally impressive 500 mg of white kidney bean 20:1 extract in each dose. Konjac Root for example swells 50X larger once it's in your stomach, meaning 3000mg adds up to about 1 and a half bagels, meaning it quite simply fills you up and as it's water that makes it swell it's 0 calorie intake. As a result, you feel less hungry. Pretty simple.

Both of these ingredients are known for their amazing appetite suppressing capabilities. This makes Hunter Burn comfortably one of the most powerful and best appetite suppressants on the market.

Vitamin D3, cayenne pepper, and green tea extract are able to enhance the effects of the other ingredients present. This means they can boost appetite suppression even more, while they add benefits like boosting energy levels, enhancing fat burning, and improving overall health.

All of this is then supported by a generous dose of l-theanine, an amino acid which will boost focus, sleep, relaxation, energy, and immunity, while reducing anxiety and stress, all of which will keep you on track.

Visit hunterevolve.com

Hunter Burn is the best appetite suppressant supplement on the market. Its high dose of glucomannan on its own would make it a strong favourite, then the addition of white kidney bean extract makes it easily the strongest appetite suppressant you will find. 

With the other ingredients in the formula helping to burn fat directly, boost your energy levels, exercise performance, and recovery, while improving your overall health, it can offer incredible support throughout every stage of your weight loss journey. 

Customers Hunter Burn Appetitie Suppressant Reviews

Customers generally give Hunter fantastic ratings, they also don't use unrealistic before and after photos and keep their claims plausable. This tends to lead to pretty good reviews as most people know that it's supposed to make weight loss easier, not be a magic pill. 

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Pros	Cons
Contains very high, yet still safe, doses of all of its ingredients  One of the strongest appetite suppressants on the market  Made using only high quality, clinically proven ingredients  Customer reviews are overwhelmingly positive	Some users may find it a little strong at first and take time to adapt to it

Criteria	Rating
Appetite Supressant	10/10
Craving Support	9/10
Other Benefits	8/10
Customer Satisfaction	10/10
Ingredients Quality	9/10
Value	9.5/10
Recommended	9/10

Leanbean - Most Popular Appetite Suppressant For Women

Leanbean is a fat burner designed especially for women from a range of natural ingredients popular in fat burning supplements. Its primary goals are to help women suppress appetite and cravings, lose weight, and burn stubborn fat stores. We also awarded it the best appetite suppressant for cravings. 

It comes in easy to swallow capsules, so is extremely convenient, making it quick and easy to take, either at home or on the go. It retails at either $59.99 or $47.49 for a 1 month supply, depending on the quantity you buy, working out out at $2 or $1.58 per serving, respectively. 

What Is In Leanbean? 

The main ingredient in Leanbean is glucomannan, which is included for its ability to suppress appetite and prevent over eating. 

This is then supported by other ingredients like green coffee bean extract, chromium, choline, acai berry extract, garcinia cambogia, turmeric, Bioperine, and many vitamins and minerals. 

Chromium boosts the absorption of nutrients and optimises blood glucose levels. This is then supported by choline, which also enhances muscular contractions, allowing you to train much harder towards your fitness goals. 

Vitamin B6 and vitamin B12 both encourage the effective absorption of the nutrients in your diet, while zinc can increase both your muscle building and fat loss potential by as much as 50 percent (9). 

The green coffee bean extract then adds a thermogenic effect, raising your body temperature and metabolic rate to enhance fat loss, while further boosting energy levels.

Visit Leanbean.com

Leanbean includes a number of natural ingredients that can be very beneficial to both appetite suppression and weight loss, such as glucomannan, chromium, vitamin B6, vitamin B12, and zinc. The supplement is also known to produce virtually no side effects. 

Unfortunately, most of these are present in dosages less than is desirable. The capsules are then also full of ingredients that are either unproven or have little effect on appetite suppression, such as garcinia cambogia and acai berry extract. 

Leanbean is our choice for the best appetite suppressant for women as, while it won't induce significant fat burning, it can help to control hunger and promote weight loss in a safe and gentle way that is ideal for the needs of the female body. 

Customers Leanbean Reviews

Seeing as leanbean is probably the most popular appetite suppressant that actually works, unlike certain competitors who dose glucomannan at 200mg.... the reviews are pretty good. Not as good as hunter. But, still very positive. 

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Pros	Cons
Offers a high level of appetite suppression  Uses only high quality, vegan friendly, gluten free ingredients  Boosts your metabolic rate and energy but is unlikely to cause crashes  Stimulates thermogenesis	Some users have been made to feel too warm The formula is a little mild for some people, particularly men

Criteria	Rating
Appetite Supressant	7/10
Craving Support	8/10
Other Benefits	9/10
Customer Satisfaction	10/10
Ingredients Quality	9/10
Value	8/10
Recommended	8/10

Lean PM - Best Appetite Suppressant For Sleep

Lean PM are appetite suppressant pills designed to help prevent you waking up at night and snacking. It's quite common place for people who are dieting to have difficulty getting to sleep because they're hungry and as a result eating something quick and unhealthy, undoing a lot of the good work done during the day. Whilst Hourglass and Hunter would also function reasonably well as evening hunger control pills (due to them avoiding caffeine) there are some extra ingredients along with natural appetite suppressants that help you get to sleep quicker. The other benefit of lean PM is that it's relatively cost friendly, although we should say as an overall appetite suppressant, it is the worst on this list. Along with adding some extra ingredients designed for the evening, it does miss out on a few of the best appetite suppressants to avoid anything that could disrupt sleep if you take the weight loss pills just before bed. 

What Is In Lean PM? 

Whilst the best appetite suppressants generally contain glucomannan or caffeine Lean PM avoids that. And whilst glucomannan is generally very good through the day, some people do find that it can leave their stomach slightly upset if they use it just before bed, and it's absence in Lean PM could be beneficial in these cases.

Along with a couple of B tier appetite suppressant supplements like green tea extract and L Theanine, Lean PM includes 5HTP (which has been demonstrated to be the most effective appetite suppressant for targeting cravings) and a host of great sleep aids. Adding melatonin in means that if you typically struggle to get to sleep because you feel hungry this will help you doze off, and from there the natural appetite suppressants in Lean PM should help keep you asleep. 

Lean PM does work as a natural appetite suppressant, although it isn't as good as the others on this list overall. It would work well as a top up to some of the other appetite suppressant supplements although we would only recommend it if your specific issue is that you struggle to get to sleep whilst dieting. There are a lot of natural appetite suppressants that are better than LeanPM, but not all too many that include melatonin, magnesium or other supplements to help OTC hunger control pills promote restful sleep.

Customers LeanPM Reviews

As an appetite suppressant Lean PM is pretty good, unfortunately they market themselves as a "fat burner" which does mean they open themselves up to a lot of negative reviews. A lot of people do complain about this, however for people who buy them as appetite suppressant supplements and to sleep more effectively were quite positive. The overall averages were actually quite positive.

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Pros	Cons
Best appetite suppressants for midnight snackers Not too expensive	Other supplements are better for every other use case No Glucomannan

Criteria	Rating
Appetite Supressant	6/10
Craving Support	8/10
Other Benefits	9/10
Customer Satisfaction	8/10
Ingredients Quality	7/10
Value	8/10
Recommended	7/10

Perscription Appetite Suppressants

Now that we've looked at the commercially available options, which should be more than enough for most cases, let's take a look at the medical options.

Diethylpropion (Tenuate dospan®) - Diethylpropion is a prescription appetite suppressant that affects the central nervous system, reducing hunger and promoting weight loss. It is typically used for short-term management of obesity. 


Liraglutide (Saxenda®) - Liraglutide is an injectable medication that mimics a hormone called glucagon-like peptide-1 (GLP-1). It helps regulate blood sugar levels and can also lead to weight loss as a side effect. Liraglutide is usually prescribed for individuals with a body mass index (BMI) of 30 or higher. 


Naltrexone-Bupropion (Contrave®) -  Naltrexone-bupropion is a combination medication that targets both the brain's reward system and the hunger signals. It helps reduce food cravings and promotes weight loss. This prescription appetite suppressant is typically used in conjunction with a reduced-calorie diet and increased physical activity. 


Phendimetrazine (Prelu-2®) - Phendimetrazine is a stimulant that affects the central nervous system, decreasing appetite and promoting weight loss. It is prescribed for short-term use to help individuals with obesity or overweight kickstart their weight loss journey. 


Phentermine (Pro-Fast®) - Phentermine is one of the most commonly prescribed appetite suppressants. It works by suppressing appetite and increasing metabolism, making it easier to lose weight. Phentermine is typically used for short-term weight loss in individuals with a BMI of 30 or higher. 


Phentermine/Topiramate (Qsymia®) - Phentermine/topiramate is a combination medication that works by suppressing appetite and increasing feelings of fullness. It is often prescribed to individuals with a BMI of 30 or higher or those with a BMI of 27 or higher with weight-related comorbidities. 

It is important to note that orlistat (Alli®), although commonly associated with weight loss, is not an appetite suppressant. It works by blocking fat absorption in the intestines and is available over-the-counter.

Final Thoughts On The Best Appetite Suppressant Supplements 

The best appetite suppressants are the supplements that can completely make you forget about your hunger. These will virtually guarantee you can stick to your planned diet and calorie intake, making it as easy as possible to see results. 

Hunter Burn is our pick as the best appetite suppressant on the market today, as the incredibly generous doses of its active ingredients will stimulate the maximum level of effectiveness possible from a safe, natural supplement. 

Provided you have a suitable diet and exercise routine already planned out to follow, Hunter Burn will give you everything you could possibly expect from appetite suppressant pills, to make your weight loss journey as quick, easy, and painless as possible.