Owning a dog is one of life’s most rewarding experiences. Their energy, loyalty, and unconditional love brighten our days—so when they start to slow down, it’s only natural we want to help. Many turn towards joint supplements to help for this, but how are you supposed to know who to trust when they’re all saying the same things?
With our years of industry experience and expertise, we wanted to offer a nuanced look to see which supplements are really worth your time. Today, we’re taking a look at Vetzyme, a staple in affordable pet care.
If you’re looking for a quick answer then no, we do not recommend this product. Vetzyme’s strength is in its affordability, but that’s also where its limitations begin. Instead we’d recommend you try FetchAgain, which offers much more comprehensive coverage to keep your dog spry, or get them back on their feet again after an accident.
Let’s find out more about why this is the case
Pros & Cons
Pros:
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Very affordable, widely available
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Offers basic joint and coat support
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Trusted legacy brand with decades of use
Cons:
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Outdated formulations lacking modern, bioavailable ingredients
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Does not include MSM, probiotics, CoQ10, or digestive enzymes
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Limited in scope: mostly focused on joints and coat, with no broader health support
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Tablets can be difficult for some dogs to accept compared to soft chews
Ingredients & Effectiveness
Glucosamine
A key joint support ingredient, but present in relatively low doses, and often not paired with other synergistic compounds like MSM or Chondroitin.
B Vitamins
Vetzyme is well known for its B-vitamin-rich formulas, which support energy levels and skin health, but it lacks broader vitamin and mineral coverage.
Cod Liver Oil
A time tested joint supplement, it’s been known to reduce soreness and stiffness in joints, helping to keep them lubricated and running smoothly.
Why FetchAgain Is a Superior Alternative
Looking at the two formulas here, you can see there’s a decent amount of overlap. At least that is to say that FetchAgain contains the same ingredients - and a lot more.
Vetzyme offers B vitamins, which of course are excellent for overall health, but FetchAgain offers over 13 essential vitamins. Vetzyme offers Glucosamine, which has very promising clinical data, at least when paired with chondroitin, which FetchAgain offers at the proper dosage. Finally is cod liver oil, and here there’s not much to say - it’s just cod liver oil, and it’s great for keeping joints lubricated and running smoothly.
FetchAgain just keeps going though, with Coenzyme10 that reduces pain and helps repair cartilage degradation. There’s also OptiMSM, which is the most bioavailable form of MSM, meaning the regular reduction to pain and swelling is much more pronounced here. To go even further beyond, FetchAgain includes blends of probiotics and digestive enzymes to help your dog digest and absorb important nutrients from their diets, keeping them young, spry and playful for much longer.
Many joint supplements for dogs offer good joint care, but none come close to FetchAgain. We highly recommend you try this one out, it really is the best out there.
Frequently Asked Questions
How do joint supplements work for dogs?
Joint supplements work by providing the body with key nutrients that help maintain the structural integrity of cartilage, reduce inflammation, and support the natural repair processes in the joints. Glucosamine and chondroitin help to rebuild cartilage and protect it from further breakdown, while omega-3 fatty acids reduce inflammation that can contribute to pain and stiffness. MSM supports connective tissue health and may help alleviate joint discomfort. Together, these ingredients can improve your dog’s mobility and quality of life, particularly as they age.
When should I start giving my dog joint supplements?
It's often recommended to start joint supplements before your dog shows visible signs of discomfort, particularly for breeds that are prone to joint issues. Many veterinarians suggest starting preventive supplementation in middle-aged or large-breed dogs, or earlier if your dog is highly active or has a history of joint problems. Starting early may help delay the onset of arthritis and other degenerative joint conditions.
Are joint supplements safe for all dogs?
In general, joint supplements are considered safe for most dogs, especially those made with high-quality, veterinary-approved ingredients. However, just like with any supplement or medication, some dogs may experience mild side effects such as gastrointestinal upset. It’s important to consult with your veterinarian before introducing any new supplement, especially if your dog has underlying health conditions or is currently taking other medications.
How long does it take for joint supplements to work?
The effects of joint supplements are usually gradual rather than immediate. Most dog owners begin to notice improvements in mobility and comfort within four to six weeks of consistent use. However, the timeline can vary depending on the severity of the joint issue, the supplement formulation, and your dog’s individual response.
Can puppies take joint supplements?
While puppies don’t typically need joint supplements, there may be exceptions in certain cases, such as those with inherited joint issues like hip dysplasia or those recovering from orthopedic surgery. Always consult your veterinarian before giving joint supplements to a growing puppy, as their developing bodies have different needs than adult dogs.
What Should I Look Out for When Purchasing a Dog Joint Supplement?
Choosing the right joint supplement for your dog can make a significant difference in their mobility, comfort, and long-term joint health. With many options on the market, it’s important to know what to look for in terms of ingredients, quality, and manufacturer credibility.
Ingredient Effectiveness and Dosage
Start by examining the active ingredients and their dosages. A quality joint supplement typically contains proven components like glucosamine, chondroitin, MSM (methylsulfonylmethane), and omega-3 fatty acids such as EPA and DHA. These ingredients are widely recognized for their ability to support cartilage health, reduce inflammation, and improve joint function. Hyaluronic acid is another valuable addition, as it supports joint lubrication. The effectiveness of a supplement depends not only on the presence of these ingredients but also on whether they are included in therapeutic dosages.
Manufacturing Standards and Quality Control
Look for supplements manufactured in facilities that follow Good Manufacturing Practices (GMP) or are certified by reputable third-party organizations. Products made in countries with strict quality regulations, such as the United States or members of the European Union, are more likely to meet safety and efficacy standards. Transparent labeling is also a good sign; avoid products that use vague terms or fail to list exact ingredient amounts.
Veterinary Endorsement and Scientific Support
Supplements recommended or formulated by veterinarians often provide an added level of trust. It’s beneficial to choose a product that has been tested in clinical studies or at least reviewed by veterinary professionals. Although not all supplements are backed by formal research, those that are tend to stand out in terms of reliability and effectiveness.
Palatability and Ease of Use
Your dog’s willingness to take the supplement matters just as much as its formulation. Consider whether the product is available in a form your dog will readily accept, such as flavored chews, powders, or liquids. A highly effective supplement won’t help if your dog refuses to take it consistently.
Product Reputation and Customer Feedback
Lastly, take time to research customer reviews and brand reputation. A consistent track record of positive feedback can help reassure you that the supplement has worked well for other dogs with similar joint issues. However, it's wise to balance anecdotal evidence with clinical guidance from your veterinarian.
Verdict
Vetzyme may still appeal to dog owners looking for a low-cost, basic supplement—but in today’s world, your dog deserves better. When compared side by side, FetchAgain is light-years ahead, offering more advanced ingredients, better absorption, and full-body benefits that go far beyond just joints.
If your goal is to keep your dog active, happy, and healthy from puppy to senior years, FetchAgain is a clear winner—and a smart investment in your dog’s future.