NuvoFlex Ingredients
Vitamin C - At 100% of your RDI this isn't an awful inclusion Vitamin C [5] plays a crucial role in collagen synthesis and has demonstrated some moderate effectiveness in treating certain types of arthritis and musculoskeletal pain relief. {2] Although if you're looking for a simple supplement, omega 3 [6] or vitamin D [7] are both more useful for joint pain and in many cases have been shown to be more effective than over the counter pain options.
Fruite-X (Calcium fructoborate and boron) 220mg - Calcium fructoborate is only about 5% calcium [1], the rest is boron and fructose (aka fruit sugar). So we're not going to be getting nearly calcium enough from this to actually do anything as we're talking 10mg and your RDI is 1200mg. [8] As for the 6mg of boron this could have some potential impact. [9] 10mg of boron has been shown to have some benefit to arthritis symptoms since the 1960's. Again it's not the most effective ingredient, but it's at least got a reasonable amount of backing. [10]
Pro collagen complex 93mg - The Pro collagen complex is made up of alma extract and icariside ii, neither of which are particularly great ingredients for a cartilage or joint pain relief supplement. Mostly because there's no evidence that they're actually going to do anything. Especially when Nuvoflex are suggesting that they'll help stimulate collagen production.
Alma Extract - The claim is that Amla fruit extract helps prevent collagen degradation in the joints, promoting cartilage growth and flexibility. There's no evidence for this at all. There's some evidence that it does function as an anti oxidant, [11] which can have some benefits for joint pain, but there are numerous better options that actually contain compounds which can reduce inflammation markers.
Icariside ii - There are some very lofty claims around Icariside ii and almost no evidence to support it's use as a joint health supplement. There is two studis, yes two, one that suggests that icariside ii can improve bone marrow stem cell quality, in beagles. Yes the dog. [12] And another that shows when mixed with hyaluronic acid and injected into the site it can improve cartilage health in rabbits. [13] Although this was not tested against hyaluronic acid alone which has been shown to have a positive impact by itself when injected into the joints. [14] It's possible that it could have some implications for humans, but the dosage that was given to the 20lb dog is more than would in the Nuvoflex blend. So even if it did manage to transfer to humans, then there isn't really going to be enough.
So as we can see there's almost no backing that the dietary supplement is going to do much to relieve pain or restore youthful cartilage as it claims.
It's not as if there's a shortage of ingredients that can improve joint inflammation, that have dozens of clinical trials that have actually been placebo controlled on humans, so we're really not sure what nuvoflex were thinking with this supplement. Both Alma and Icarside have been studied for other properties, but there isn't really much to suggest that they're going to be effective for joint tissue restoration.
NuvoFlex FAQ
Is Nuvoflex A Scam?
Considering that they promise to help you regrow cartialage, we'd say that Nuvoflex is leaning towards being a scam. It will technically do something a for joints so it's not a complete one. But, it's close.
Does Nuvoflex Have A Money Back Guarantee?
Nuvoflex claims to have a money back guarantee, but there are complaints on BBB and Trustpilot that they do not honor it.
References
1 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256803/
2 - https://pubmed.ncbi.nlm.nih.gov/7889887/
3 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543556/
4 - https://www.bbb.org/us/nv/incline-village/profile/vitamins-and-supplements/juvenon-llc-1166-90021922
5 - https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/
6 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362115/
7 - https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/
8 - https://ods.od.nih.gov/factsheets/Calcium-HealthProfessional/
9 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712861/
10 - https://ods.od.nih.gov/factsheets/Boron-HealthProfessional/
11 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878900/
12 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503000/
13 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610878/
14 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469223/
15 - https://www.nccih.nih.gov/health/glucosamine-and-chondroitin-for-osteoarthritis
16 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7812094/
17 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372953/
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