ProJoint Plus Review Pros & Cons
Projoint Plus Ingredients
1500 mg of Glucosamine Sulfate – This is a good dose of glucosamine as we mentioned in the introduction and a solid start for ProJoint Plus. The fact is that this is the backbone of a lot of mid range supplements. It’s mostly been trialed for knee pain in osteoarthritis specifically. [4] The natural compound found in cartilage has even been prescribed in many countries, and is generally well tolerated. Most studies suggest that it helps reduce joint pain, but doesn’t really do much for mobility of joint health in general.
200 mg of Boswellia Serrata Extract – Boswellia is mostly used as an anti inflammatory and most clinical trials show it to be at least moderately effective, again it’s a common ingredient for mid range joint supplements and 200mg is the clinically studied dose. [2]
150 mg of Chondroitin Sulfate – Chondroitin is a little bit more mixed, with most positive studies showing that it does increase the efficacy of Glucosamine Sulfate. [5] However, it doesn’t really do anything by itself and is normally dosed a bit higher than it is in ProJoint Plus.
150 mg of Turmeric – Curcumin, the extract from Turmeric that works as an anti inflammatory is great as a joint health supplement ingredient. [3,6] Unfortunately, you need way more of it than is in here. Realistically more than 30x the amount in Projoint Plus.
25 mg of Quercetin – Quercetin is an interesting choice, the studies are mixed although leaning slightly to the positive in terms of reducing joint pain and inflammation. [7] The problem we have here is that functional doses are 250-1000mg meaning that the amount in Projoint plus isn’t going to do anything.
25 mg of Methionine – The standard dose of methionine is 200mg four times a day. So, once again we’re not even close to the effective range. [8] Methionine is an anti oxidant meaning that it can have some benefits for joint health, but not at this dose.
25 mg of MSM (Methylsulfonylmethane) – A lot of joint supplements contain MSM, and even some of the good ones fall prey to having to throw it in for marketing purposes. The fact is that you need grams of this for it to be effective, not 25mg. [9]
25 mg of Bromelain – Bromelain is an enzyme found in pineapples. Interestingly the way it works is by stopping your body from producing inflammatory compounds. It binds to the precursors meaning that they can’t actually be turned into prostaglandins which cause inflammation. Instead it creates cytokines which have the opposite effect. The problem is that you need 100mg or more for it to do anything. [10]
References
1 - https://www.nccih.nih.gov/health/glucosamine-and-chondroitin-for-osteoarthritis
2 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309643/
3 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664031/
4 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097075/
5 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035477/
6 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664031/
7 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808895/
8 - https://pubmed.ncbi.nlm.nih.gov/28929442/
9 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372953/
10 - https://www.nccih.nih.gov/health/bromelain
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